Tim Wehner

1994 – 2001
Studium der Humanmedizin, Universität Witten/Herdecke, Auslandsaufenthalte in Aberdeen, UK, und Cleveland, OH, USA
Promotion zum Dr. med., Abteilung für experimentelle Neurologie, Charité, Berlin, Prof. Dr. U. Dirnagl
2001 – 2002
Wissenschaftlicher Mitarbeiter, Studiendekanat, Universität Witten/Herdecke; Mitarbeit bei der Etablierung des Reformstudiengangs Medizin
2002 – 2011
Weiterbildung zum Neurologen und Epileptologen, MetroHealth Medical Center, Cleveland, OH, USA (2002 – 2003), Cleveland Clinic, Cleveland, OH, USA (2003 – 2008), Universitätsklinikum Marburg (2008 – 2011), Vitos-Klinik für Psychiatrie, Marburg (2010)
Diplom, American Board of Psychiatry und Neurology
Facharzt für Neurologie
2011 – 2017
Consultant Neurologist and Clinical Neurophysiologist, and Honorary Senior Lecturer, Department of Clinical and Experimental Epilepsy, National Hospital for Neurology and Neurosurgery, University College London, London, UK
Seit Februar 2017
Oberarzt der Ruhr-Epileptologie an der Neurologischen Klinik
Ellen Thomas Award for Epilepsy Research

Dt. Gesellschaft für Epileptologie (Zertifikat Epileptologie plus)

Dt. Gesellschaft für klinische Neurophysiologie (EEG-Zertifikat)

Dt. Gesellschaft für Neurologie

Seit 2003
Vorlesungen, Seminare, und Unterricht am Krankenbett im Rahmen des Medizinstudiums.
Praktikum Neurologie (6. und 10. Semester)
PJ – Beauftragter der Neurologischen Klinik
Faculty, Biannual ILAE Teaching Course for Epilepsy, Oxford, UK

Wehner T, Mannan S, Turaga S, Vallabhaneni K, Yip HM, Wiggans C, Shankar R,Duncan JS, Sander JW. Retention of perampanel in adults with pharmacoresistant epilepsy at a single tertiary care center. Epilepsy Behav. 2017; 73:106-10.

Sparks R, Vakharia V, Rodionov R, Vos SB, Diehl B, Wehner T, Miserocchi A,McEvoy AW, Duncan JS, Ourselin S. Anatomy-driven multiple trajectory planning (ADMTP) of intracranial electrodes for epilepsy surgery. Int J Comput Assist Radiol Surg. 2017; 12:1245-55.

Aurangzeb S, Symmonds M, Knight RK, Kennett R, Wehner T, Irani SR. LGI1-antibody encephalitis is characterised by frequent, multifocal clinical and subclinical seizures. Seizure. 2017; 50:14-7.

Shankar R, Henley W, Wehner T, Wiggans C, McLean B, Pace A, Mohan M, Sadler M, Doran Z, Hudson S, Allard J, Sander JW. Perampanel in the general population and in people with intellectual disability: Differing responses. Seizure. 2017; 49:30-5.

Sharma NK, Pedreira C, Centeno M, Chaudhary UJ, Wehner T, França LGS, Yadee T, Murta T, Leite M, Vos SB, Ourselin S, Diehl B, Lemieux L. A novel scheme for the validation of an automated classification method for epileptic spikes by comparison with multiple observers. Clin Neurophysiol. 2017; 128:1246-54.

Gooneratne IK, Mannan S, de Tisi J, Gonzalez JC, McEvoy AW, Miserocchi A, Diehl B, Wehner T, Bell GS, Sander JW, Duncan JS. Somatic complications of epilepsy surgery over 25 years at a single center. Epilepsy Res. 2017; 132:70-7.

Gollwitzer S, Scott CA, Farrell F, Bell GS, de Tisi J, Walker MC, Wehner T, Sander JW, Hamer HM, Diehl B. The long-term course of temporal lobe epilepsy: From unilateral to bilateral interictal epileptiform discharges in repeated video-EEG monitorings. Epilepsy Behav. 2017; 68:17-21.

Carreño M, Bien CG, Asadi-Pooya AA, Sperling M, Marusic P, Elisak M, Pimentel J, Wehner T, Mohanraj R, Uranga J, Gómez-Ibáñez A, Villanueva V, Gil F, Donaire A, Bargalló N, Rumià J, Roldán P, Setoain X, Pintor L, Boget T, Bailles E, Falip M, Aparicio J, Dalmau J, Graus F. Epilepsy surgery in drug resistant temporal lobe epilepsy associated with neuronal antibodies. Epilepsy Res. 2017; 129:101-5.

Nowell M, Sparks R, Zombori G, Miserocchi A, Rodionov R, Diehl B, Wehner T, White M, Ourselin S, McEvoy A, Duncan J. Resection planning in extratemporal epilepsy surgery using 3D multimodality imaging and intraoperative MRI. Br J Neurosurg. 2016; 8:1-3.

Franko E, Wehner T, Joly O, Lowe J, Porter MC, Kenny J, Thompson A, Rudge P, Collinge J, Mead S. Quantitative EEG parameters correlate with the progression of human prion diseases. J Neurol Neurosurg Psychiatry. 2016; 87:1061-7.

Sparks R, Zombori G, Rodionov R, Nowell M, Vos SB, Zuluaga MA, Diehl B, Wehner T, Miserocchi A, McEvoy AW, Duncan JS, Ourselin S. Automated multiple trajectory planning algorithm for the placement of stereo-electroencephalography (SEEG) electrodes in epilepsy treatment. Int J Comput Assist Radiol Surg. 2017; 12:123-36.

Gollwitzer S, Valente I, Rodionov R, Scott C, Ritter LM, Wehner T, Hamer HM, Bartolomei F, Diehl B. Visual and semiautomated evaluation of epileptogenicity in focal cortical dysplasias - An intracranial EEG study. Epilepsy Behav. 2016; 58:69-75.

Whitehead K, Gollwitzer S, Millward H, Wehner T, Scott C, Diehl B. The additional lateralizing and localizing value of the postictal EEG in frontal lobe epilepsy. Clin Neurophysiol.2016; 127:1774-80.

Nowell M, Sparks R, Zombori G, Miserocchi A, Rodionov R, Diehl B, Wehner T, Baio G, Trevisi G, Tisdall M, Ourselin S, McEvoy AW, Duncan J. Comparison of computer-assisted planning and manual planning for depth electrode implantations in epilepsy. J Neurosurg. 2015 4:1-9.

Varley J, Wehner T, Sisodiya S. Diaphragm myoclonus followed by generalized atonia in a patient with trisomy 4p: unusual semiology in an unusual condition. Epileptic Disord. 2015 Dec;17:473-7.

Baraldi S, Farrell F, Benson J, Diehl B, Wehner T, Kovac S. Drop attacks, falls and atonic seizures in the Video-EEG monitoring unit. Seizure. 2015; 32:4-8.

Fois C, Kovac S, Khalil A, Tekgöl Uzuner G, Diehl B, Wehner T, Duncan JS, Walker MC. Predictors for being offered epilepsy surgery: 5-year experience of a tertiary referral centre. J Neurol Neurosurg Psychiatry. 2016 ;87:209-11.

Nowell M, Rodionov R, Zombori G, Sparks R, Winston G, Kinghorn J, Diehl B, Wehner T, Miserocchi A, McEvoy AW, Ourselin S, Duncan J. Utility of 3D multimodality imaging in the implantation of intracranial electrodes in epilepsy. Epilepsia. 2015; 56:403-13.

Kovac S, Diehl B, Wehner T, Fois C, Toms N, Walker MC, Duncan JS. Gelastic seizures: incidence, clinical and EEG features in adult patients undergoing video-EEG telemetry. Epilepsia. 2015;56:e1-5.

Wehner T, Chinnasami S, Novy J, Bell GS, Duncan JS, Sander JW. Long term retention of retigabine in a cohort of people with drug resistant epilepsy. Seizure. 2014; 23:878-81.

Nowell M, Rodionov R, Diehl B, Wehner T, Zombori G, Kinghorn J, Ourselin S, Duncan J, Miserocchi A, McEvoy A. A Novel Method for Implementation of Frameless StereoEEG in Epilepsy Surgery. Neurosurgery. 2014; 10 Suppl 4:525-33.

Perumal MB, Chinnasami S, Shah A, Rodionov R, Maglajlija V, Miserocchi A, McEvoy AW, Wehner T, Diehl B. Epileptic kinetopsia localizes to superior parietal lobule and intraparietal sulcus. Neurology. 2014; 83:768-70.

Kovac S, Chaudhary UJ, Rodionov R, Mantoan L, Scott CA, Lemieux L, Wehner T, Scherg M, Diehl B. Ictal EEG source imaging in frontal lobe epilepsy leads to improved lateralization compared with visual analysis. J Clin Neurophysiol 2014; 31:10-20.

Kovac S, Rodionov R, Chinnasami S, Wehner T, Scott CA, McEvoy AW, Miserocchi A, Diehl B. Clinical significance of nonhabitual seizures during intracranial EEG monitoring. Epilepsia 2014; 55:e1-5.

Unnwongse K, Alexopoulos AV, Busch RM, Wehner T, Nair D, Bingaman WE, Najm IM. Nonlesional atypical mesial temporal epilepsy: electroclinical and intracranial EEG findings. Neurology 2013; 81:1848-55.

Chapin JS, Busch RM, Silveira DC, Wehner T, Naugle RI, Ferguson L, Najm IM. Memory performance in older adults before and after temporal lobectomy for pharmacoresistant epilepsy. Clin Neuropsychol. 2013; 27:1316-27.

Rodionov R, Vollmar C, Nowell M, Miserocchi A, Wehner T, Micallef C, Zombori G, Ourselin S, Diehl B, McEvoy AW, Duncan JS. Feasibility of multimodal 3D neuroimaging to guide implantation of intracranial EEG electrodes. Epilepsy Res. 2013; 107:91-100.

Teotónio R, Rodionov R, McEvoy AW, Duncan J, Diehl B, Wehner T. Ictal unilateral hyperkinetic proximal lower limb movements: an independent lateralising sign suggesting ipsilateral seizure onset. Epileptic Disord. 2013; 15:142-7.

Kovac S, Nachev P, Rodionov R, Scott C, McEvoy AW, Toms N, Wehner T, Duncan JS, Diehl B. Neck atonia with a focal stimulation-induced seizure arising from the SMA: Pathophysiological considerations. Epilepsy and Behavior 2012; 24:503-6.

Busch RM, Floden D, Lineweaver TT, Chapin JS, Unnwongse K, Wehner T, Diaz-Arrastia R, Najm IM. Effect of apolipoprotein ε4 allele on hippocampal and brain volume in intractable temporal lobe epilepsy. Epilepsy and Behavior 2011; 21:88-90.

Wehner T, Lachhwani DK, Bingaman W, Haspolat S, Gupta A, Kotagal P, Tuxhorn I, Wyllie E. Epilepsy surgery outcome in coexisting symptomatic refractory focal epilepsy and benign focal epilepsy of childhood. Pediatric Neurology 2011; 44:52-56.

O'Dwyer R, Wehner T, Lapresto E, Ping L, Tkach J, Noachtar S, Diehl B. Differences in corpus callosum volume and diffusivity between temporal and frontal lobe epilepsy. Epilepsy and Behavior 2010; 19:376-82.

Unnwongse K, Wehner T, Bingaman W, Foldvary-Schaefer N. Gelastic seizures and the anteromesial frontal lobe: A case report and review of intracranial EEG recording and electrocortical stimulation case studies. Epilepsia 2010; 51:2195-8.

Wehner T, Bauer S, Hamer HM, Hattemer K, Immisch I, Knake S, Nowak M, Reif PS, Strzelczyk A, Rosenow F. Six months postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany. Epilepsy and Behavior 2009; 16:423-5.

Syed TU, Arozullah AM, Suciu GP, Toub J, Kim H, Dougherty ML, Wehner T, Stojic A, Syed I, Alexopoulos AV: Do observer and self-reports of ictal eye closure predict psychogenic nonepileptic seizures? Epilepsia 2008; 49:898-904.

Wehner T, LaPresto E, Tkach J, Liu P, Bingaman W, Prayson RA, Ruggieri P, Diehl B: The value of interictal diffusion weighted imaging in lateralizing temporal lobe epilepsy. Neurology 2007; 68:122-7.

Wehner T, Ross JS, Ransohoff RM: Fluid in the Flute – Reversible Hydromyelia. Journal of the Neurological Sciences 2005;236:85-6.

Wehner T, Bontert M, Eyupoglu I, Prass K, Prinz M, Klett FF, Heinze M, Bechmann I, Nitsch R, Kirchhoff F, Kettenmann H, Dirnagl U, Priller J: Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. Journal of Neuroscience 2003;23:5004-11.

Priller J, Flugel A, Wehner T, Boentert M, Haas CA, Prinz M, Fernandez-Klett F, Prass K, Bechmann I, de Boer BA, Frotscher M, Kreutzberg GW, Persons DA, Dirnagl U: Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment. Nature Medicine 2001; 7:1356-61.

Bechmann I, Priller J, Kovac A, Böntert M, Wehner T, Fernandez-Klett F, Bohsung J, Stuschke M, Dirnagl U, Nitsch R: Immune surveillance of mouse brain perivascular spaces by blood-borne macrophages. European Journal of Neuroscience 2001; 14:1651-58.

Grönheit W, Popkirov S, Wehner T, Schlegel U and Wellmer J (2018) Practical Management of Epileptic Seizures and Status Epilepticus in Adult Palliative Care Patients. Front. Neurol. 9:595. doi: 10.3389/fneur.2018.00595


Irmen F, Wehner T, Lemieux L. Do reflex seizures and spontaneous seizures form a continuum? - triggering factors and possible common mechanisms. Seizure 2015 ;25:72-9.

Wehner T. The role of functional imaging in the tumor patient. Epilepsia. 2013 54 S9:44-9.

Unnwongse K, Wehner T, Foldvary-Schaefer N. Mesial frontal lobe epilepsy. Journal of Clinical Neurophysiology. 2012; 29:371-8.

Unnwongse K, Wehner T, Foldvary-Schaefer N. Selecting patients for epilepsy surgery. Current Neurology and Neuroscience Report 2010; 10:299-307.

Wehner T, Hamer HM: Absetzen einer Antikonvulsivatherapie bei anfallsfreien Patienten. Neuro aktuell, 2010; 188:27-9.

Wehner T, Lüders HO: Role of Neuroimaging in the Presurgical Evaluation of Epilepsy.

Journal of Clinical Neurology 2008; 4:1-16.

Wehner T, Unnwongse K, Diehl B: Focal epilepsy. In Mills KM (editor): Oxford Textbook of Clinical Neurophysiology, Oxford University Press, 2017.

Wehner T & McEvoy A: Classification of seizures and epilepsy. In xxx (editor): Oxford Textbook of Neurosurgery, Oxford University Press, in press

Wehner T: Generalized tonic-clonic seizures. In Wyllie E (editor): The treatment of Epilepsy – Principles and Practice, 5th edition, Lippincott Williams & Wilkins, Philadelphia, 2011.

Wehner T, Knake S, Grant PE: Structural imaging of mesial temporal lobe epilepsy. In Rosenow F, Lüders H, Ryvlin P (editors): The mesial temporal lobe epilepsies, John Libbey Eurotext, Paris, 2011.

Perampanel in a real-world setting – Making Waves Series, Manchester, UK, September 2017.

How to differentiate epileptic and nonepileptic seizures on clinical grounds – Brighton, UK, December 2016.

Epilepsy – A network disease – Indian Epilepsy School, Hyderabad, Indien, September 2015.

Epilepsy – more than seizures counts – Annual Meeting of the Thai Neurological Society, Bangkok, Thailand, July 2015.

Role of functional neuroimaging in people with focal epilepsy in the setting of low grade brain neoplasms – International Epilepsy Symposium, Cleveland, OH, USA, May 2013.

Pitfalls in Epilepsy Surgery – Annual meeting of the Thai Neurological Society, Bangkok, Thailand, July 2011.

Withdrawing Anticonvulsants in People with Epilepsy who are Seizure free – Prasat Neurological Institute Grand Rounds, Bangkok, Thailand, Nov 2010.

Absetzen einer Antikonvulsivatherapie – Fortbildungsakademie der 6. gemeinsamen Jahrestagung der Deutschen, Österreichischen und Schweizerischen Sektionen der Internationalen Liga gegen Epilepsie, Rostock, Mai 2009.

Mesial Temporal Sclerosis – primary and secondary MRI criteria - 1st International Epilepsy Colloquium, Marburg, Juni 2008.

Presurgical Evaluation of Pharmacoresistant Epilepsy – Cleveland Clinic / Yeditepe University Epilepsy Course, Istanbul, Turkey, September 2007.


Klinik für Neurologie
Bochum GmbH


In der Schornau 23–25
44892 Bochum

0234 299–3993
0234 299–3739

Unterstützen Sie die Weiterentwicklung von Diagnostik und Therapien bei Epilepsien Fördern Sie die Fort- und Weiterbildung von Ärzten, Pflegern, Rettungskräften, Betreuern und Therapeuten Spenden Sie an den Förderverein Ruhr-Epileptologie.

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Förderverein Ruhr-Epileptologie e.V.
Volksbank Bochum-Witten
IBAN DE93 4306 0129 0348 2025 00

Ruhr-Epileptologie, Klinik für Neurologie,
Universitätsklinikum Knappschaftskrankenhaus
Bochum, In der Schornau 23-25, 44892 Bochum

Förderverein Ruhr-Epileptologie e.V.
Volksbank Bochum-Witten
IBAN DE93 4306 0129 0348 2025 00